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    Role of Nitric Oxide in Health and Nutrition overview by Mekdar.com
    دور النيتريك أكسيد في الصحة والتغذية ... مع مقدار

    Role of Nitric Oxide in Health and Nutrition - دور النيتريك أكسيد في الصحة والتغذية


    Nitric oxide may act beneficially by increasing blood flow and delivery of oxygen and glucose.

    Nitric oxide is a very important compound in the human body, as it plays a vital role in many important physiological functions.

    Overall, nitric oxide plays a vital role in maintaining a healthy cardiovascular system, nervous system, and immune system.

    Nitric Oxide Mekdar Waleed Foad

     

    The role of nitric oxide in the human body

    Nitric oxide is an important gaseous molecule that plays a crucial role in many physiological and pathological processes in the body. These functions include:

    1- Regulating blood flow and pressure: Nitric oxide helps dilate blood vessels, which helps improve blood flow and lower blood pressure.

    2- Maintaining vascular function: Nitric oxide protects blood vessels from sclerosis and promotes angiogenesis, or the growth of new blood vessels, which is essential for wound healing and tissue repair.

    3- Maintaining the health of the nervous system: Nitric oxide helps improve the function of the nervous system and reduce nerve inflammation.

    4- Improving immune function: Nitric oxide can boost immune system function and prevent infections.

    5- Maintaining a healthy digestive system: Nitric oxide helps improve digestive function and reduce gastritis.

    6- Improve athletic performance: Nitric oxide can improve athletic performance by improving blood flow to muscles.

    Nitric oxide can also have an antioxidant and cell growth stimulating effect

                                

    Food sources of nitric oxide

    Nitric oxide can be obtained from some foods such as dark chocolate, beets, spinach, carrots, onions, garlic, apples, bananas, red meat, chicken and fish.

    Nitric oxide can be obtained from natural foods that contain nitrates and nitrites. These compounds are converted in the body into nitric oxide. Here are some natural food sources of nitric oxide:

     

    1- Green leafy vegetables: Green leafy vegetables such as spinach, cabbage, lettuce and celery contain high levels of nitrates, which are converted into nitric oxide in the body.

    2- Root vegetables: Green roots such as carrots and beets contain high levels of nitrates, which are converted into nitric oxide in the body.

    3- Fruits: Fruits such as pomegranates, grapes, and berries contain nitrite compounds that are converted into nitric oxide in the body.

    4- Fish and seafood: Fish and seafood contain high levels of zinc and magnesium, which are substances that help produce nitric oxide.

    5- Herbs and spices: Herbs and spices such as garlic, ginger and cinnamon contain nitrates and nitrites that are converted into nitric oxide in the body.

    6-Dark Chocolate: Dark chocolate contains antioxidants and nitrites that are converted into nitric oxide in the body.

    Nitric oxide can be synthesized in the body from the amino acid arginine, which is found in protein-rich foods such as meat, poultry, fish, and dairy products.

    It should be noted that some of these foodstuffs may contain high levels of salts, which are associated with some side effects when consumed in excess

    In addition, nitric oxide can be obtained from special dietary supplements.

     

    Warning: Use nitric oxide supplements

    Nitric oxide can be obtained from some special dietary supplements. However, you should be aware that the use of nitric oxide supplements should be done under the supervision of your physician, as they can interact with some medications and cause side effects.

     

    Conclusion

    The role of Nitric oxide in Medicine and nutrition is still an active area of research, and the long-term effects of Nitric oxide supplementation are not yet fully understood. In some cases, excessive Nitric oxide production can be harmful and has been implicated in the development of various diseases, including cardiovascular disease, cancer, and neurodegenerative diseases.

     

    Scientific references

    1- Exposure Of Stored Erythrocytes To Nitric Oxide Prevents Transfusion–Associated Pulmonary Hypertension

    Stefan Muenster, Arkadi Beloiartsev, Binglan Yu, E Du, Sabia Abidi, Ming Dao, Gregor Fabry, Jan A Graw, Martin Wepler, Rajeev Malhotra, Bernadette O Fernandez, Martin Feelisch, Kenneth D Bloch, Donald B Bloch, Warren M Zapol

    Anesthesiology. Author manuscript; available in PMC 2017 Nov 1.Published in final edited form as: Anesthesiology. 2016 Nov; 125(5): 952–963.  doi: 10.1097/ALN.0000000000001294

    PMCID: PMC5069190

     

    2- Nitric oxide in acute brain injury: a pilot study of NO(x) concentrations in human brain microdialysates and their relationship with energy metabolism. Carpenter, Keri L. H., Ivan S Timofeev, Pippa G. Al-Rawi, David K. Menon, John D. Pickard and Peter John Hutchinson.  Acta neurochirurgica. Supplement 102 (2008): 207-13 .

    3- Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes

    Sevda Gheibi, Alan P. Samsonov, Shahsanam Gheibi, Alexandra B. Vazquez, Khosrow Kashfi

    Biochem Pharmacol. Author manuscript; available in PMC 2021 Jun 1.Published in final edited form as: Biochem Pharmacol. 2020 Jun; 176: 113819. Published online 2020 Jan 21.  doi: 10.1016/j.bcp.2020.113819

    PMCID: PMC7263957

    4- Role of Neuronal Nitric Oxide Synthase on Cardiovascular Functions in Physiological and Pathophysiological States

    Ahmmed Ally, Isabella Powell, Minori M. Ally, Kevin Chaitoff, Surya Nauli

    Nitric Oxide. Author manuscript; available in PMC 2021 Sep 1.Published in final edited form as: Nitric Oxide. 2020 Sep 1; 102: 52–73. Published online 2020 Jun 23.  doi: 10.1016/j.niox.2020.06.004

    PMCID: PMC7375925

    5:  Role of the Platelets and Nitric Oxide Biotransformation in Ischemic Stroke: A Translative Review from Bench to Bedside

    Maciej Bladowski, Jakub Gawrys, Damian Gajecki, Ewa Szahidewicz-Krupska, Anna Sawicz-Bladowska, Adrian Doroszko

    Oxid Med Cell Longev. 2020; 2020: 2979260.  Published online 2020 Aug 28. doi: 10.1155/2020/2979260

    PMCID: PMC7474795

     

    6:  Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism

    Veena Somasundaram, Debashree Basudhar, Gaurav Bharadwaj, Jae Hong No, Lisa A. Ridnour, Robert Y.S. Cheng, Mayumi Fujita, Douglas D. Thomas, Stephen K. Anderson, Daniel W. McVicar, David A. Wink

    Antioxid Redox Signal. 2019 Mar 10; 30(8): 1124–1143.  Published online 2019 Jan 28. doi: 10.1089/ars.2018.7527

    PMCID: PMC6354612

     

    7:  Delivery of Nitric Oxide in the Cardiovascular System: Implications for Clinical Diagnosis and Therapy

    Tianxiang Ma, Zhexi Zhang, Yu Chen, Haoran Su, Xiaoyan Deng, Xiao Liu, Yubo Fan

    Int J Mol Sci. 2021 Nov; 22(22): 12166.  Published online 2021 Nov 10. doi: 10.3390/ijms222212166

    PMCID: PMC8625126

     

     

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    Waleed Foad

    Dr. Waleed Foad

    Physician Nutrition Consultant, For 15+ years

    Master degree in Public Health, Majoring: Nutrition


    Bachelor of Medicine, Bachelor of Surgery (MBBS)


    Alexandria University, Egypt.

    Posted on
    05 Mar 2023
    by:
    Walaa Foula

    Dr. Walaa Foula

    Physician Nutrition Consultant, For 17+ years

    Doctorate degree in Public Health, Majoring: Nutrition


    Bachelor of Medicine, Bachelor of Surgery (MBBS)


    Alexandria University, Egypt.

    Posted on
    05 Mar 2023
    by:
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